Wrinkle correction can be done by using Botulinum toxin as a muscle relaxer or in combination with Dermal Fillers. Dermal fillers are soft tissue fillers, injected into the skin to help fill in facial wrinkles, thereby restoring a smoother appearance. Fillers are used in creating a smoother and or fuller appearance in the face, including, cheeks, lips and for increasing the volume of the back of the hand. Injectable fillers in some people may need more than one injection to achieve the wrinkle-smoothing effect and the effect may last for about six months or longer. Successful results depend on the health of the skin, skill of the health care provider, and type of filler used.